Lloyd Bridges plays Steven McCroskey, a character involved in overseeing the operations of the airplane.
Raymond Burr portrays Judge D.C. Simonton, a figure in the legal system who has a role in the comedic plot.
Chuck Connors plays The Sarge, a military character that adds to the film's humor.
Rip Torn takes on the dual roles of Bud Kruger and President Reagan, showcasing a comedic take on both characters.
John Dehner plays The Commissioner, a character who adds to the challenges faced by the protagonists.
Chad Everett portrays Simon Kurtz, contributing to the comedic narrative of the film.
Peter Graves plays Capt. Clarence Oveur, a captain known for his humorous interactions with passengers.
Julie Hagerty takes on the role of Elaine Dickinson, a stewardess who is central to the story's romantic subplot.
Robert Hays portrays Ted Striker, the protagonist who faces various funny predicaments.
Kent McCord plays Dave Unger, a character involved in the unfolding comedic events.
William Shatner portrays Cdr. Buck Murdock, adding a comedic twist to the military aspects of the story.
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