Demi Moore plays Claire Donnelly, a young widow who finds herself dealing with an unplanned pregnancy in 1952.
Shirley Knight portrays Mary Donnelly, Claire's mother-in-law who has her own opinions about abortion.
Catherine Keener takes on the role of Becky, a college student who becomes pregnant and seeks help from a group of friends in 1974.
Jason London plays Kevin Donnelly, Claire's young brother-in-law who is caught in the middle of the family’s drama.
CCH Pounder portrays Jenny Ford, a nurse who provides support to women seeking abortions in 1996.
Kevin Cooney plays Dr. Kramer, a doctor who performs abortions and advocates for women's reproductive rights.
Robin Gammell portrays Jim Donnelly, Claire's father-in-law who struggles with accepting her decision.
Phyllis Lyons takes on the role of Audrey, a nurse who works with Dr. Kramer and provides care to women at the clinic.
Aaron Lustig plays Tom, a sympathetic neighbor who supports Claire during a difficult time.
Dena Burton portrays Young Nurse, a nurse who assists at the clinic and cares for the women undergoing procedures.
Marie DeCicco plays Annie Ross, a woman who shares her own story of abortion with Claire.
Lorna Scott portrays Louise, a friend of Claire's who offers her support and understanding.
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