Richard Dreyfuss plays Prof. James Krippendorf, a father and anthropologist who fabricates a New Guinea tribe to continue his academic career.
Jenna Elfman portrays Veronica, a TV researcher and single mother who becomes involved with Prof. Krippendorf's fabricated tribe.
Zakes Mokae stars as Sulukim, a colleague of Prof. Krippendorf who assists in the elaborate deception.
Siobhan Fallon Hogan is Lori, a colleague of Prof. Krippendorf who questions his unusual research methods.
Natasha Lyonne plays Shelly, one of Prof. Krippendorf's children, who gets involved in the creation of the fake tribe.
Gregory Smith portrays Mickey, one of Prof. Krippendorf's children, who joins in the fabrication of the imaginary tribe.
Lily Tomlin is Ruth Allen, a fellow anthropologist who becomes suspicious of Prof. Krippendorf's research.
Stephen Root plays Gerald Adams, a colleague of Prof. Krippendorf who unwittingly gets caught up in the tribal deception.
Elaine Stritch portrays Irene Hargrove, a university dean who is skeptical of Prof. Krippendorf's tribe project.
Mila Kunis stars as Abbey Tournquist, a student of Prof. Krippendorf who becomes involved in the fabricated tribal research.
David Ogden Stiers is Henry Spivey, a colleague of Prof. Krippendorf who questions the validity of the Papua New Guinea tribe.
Doris Belack plays President Porter, a university figurehead who becomes unwittingly swept up in Prof. Krippendorf's tribal charade.
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