Bob Hearts Abishola

Billy Gardell portrays the main character, Bob Wheeler, in Bob Hearts Abishola. Bob is a middle-aged, working-class man from Detroit who suffers a heart attack and becomes infatuated with his nurse, Abishola. As the story unfolds, Bob must learn to navigate the differences in culture and background between himself and Abishola.

Folake Olowofoyeku plays the role of Abishola Adebambo, the Nigerian nurse who captures Bob's heart. Abishola is an intelligent and independent woman who immigrated to the United States for a better life. She is a dedicated nurse and is hesitant to become involved with Bob due to their contrasting backgrounds.

Gina Yashere portrays Kemi, Abishola's friend and coworker. Kemi is a fellow nurse who hails from Nigeria. She provides comedic relief and offers advice and support to Abishola throughout her relationship with Bob.

Christine Ebersole plays the role of Dottie Wheeler, Bob's mother. Dottie is a wealthy American woman who has a close relationship with her son. She is skeptical of Bob's infatuation with Abishola but eventually begins to warm up to her.

Matt Jones portrays Douglas Wheeler, Bob's younger brother. Douglas is a good-hearted but somewhat eccentric character who supports his brother's pursuit of Abishola. He adds comedic elements to the show with his unique personality.

Maribeth Monroe plays the role of Christina Wheeler, Bob's sister. Christina is a caring and outspoken woman who is fiercely protective of her family. She initially has reservations about Bob's relationship with Abishola but eventually learns to accept and support them.

Shola Adewusi portrays Auntie Olu, Abishola's aunt, who lives with her in America. Auntie Olu is a traditional Nigerian woman who provides cultural context and humor to the show. She often expresses her opinions and offers guidance to Abishola.

Barry Shabaka Henley plays the role of Uncle Tunde, Abishola's uncle. Uncle Tunde is a respected member of the Nigerian community in America. He is supportive of Abishola's ambitions and offers wise advice to her.