Cast of The Orville

Seth MacFarlane portrays the lead character, Ed Mercer, the recently divorced officer who is given command of the U.S.S. Orville. As the captain, Ed tries to maintain a professional demeanor while dealing with personal and professional obstacles.

Adrianne Palicki plays Kelly Grayson, the First Officer of the U.S.S. Orville and Ed Mercer's ex-wife. Despite their complicated history, Kelly remains a valuable member of the crew and maintains a professional relationship with Ed.

Penny Johnson Jerald portrays Claire Finn, the Chief Medical Officer of the U.S.S. Orville. Driven and passionate about her work, Claire often finds herself balancing her personal life with the demands of her profession.

Scott Grimes plays Gordon Malloy, the helmsman of the U.S.S. Orville. Known for his laid-back and humorous nature, Gordon brings levity to the ship's crew while also displaying impressive piloting skills.

Peter Macon portrays Bortus, the second officer and a member of the Moclan species. Bortus is known for his stoic and serious demeanor, often providing a contrasting perspective to the rest of the crew.

Jessica Szohr plays Talla Keyali, the replacement First Officer on the U.S.S. Orville. Talla is known for her determined and no-nonsense attitude, which often leads to unique problem-solving approaches.

J. Lee portrays John LaMarr, the navigator and helmsman of the U.S.S. Orville. John is known for his technical expertise and sense of humor, often providing comic relief in tense situations.

Mark Jackson plays Isaac, an artificial lifeform and the Science and Engineering Officer of the U.S.S. Orville. Isaac brings a unique perspective to the crew and often explores the ethical implications of artificial intelligence.