Full Frontal with Samantha Bee (TV) Cast
The cast of Full Frontal with Samantha Bee. Updated on October 7, 2025.
136 actors
Samantha Bee
as Self - Host (218 episodes)
Sigourney Weaver
as Sigourney Weaver (1 episode)

Sigourney Weaver is a renowned actress known for her iconic roles in films such as Alien and Ghostbusters. On Full Frontal with Samantha Bee, Weaver made a guest appearance as herself, bringing her charisma and wit to the show's comedic commentary.

Sarah Silverman
as Self (1 episode)

Sarah Silverman is a talented comedian, actress, and writer. On Full Frontal with Samantha Bee, Silverman made an appearance as herself, adding her unique humor and perspective to the show's satirical take on current events.

Andy Cohen
as Self (1 episode)

Andy Cohen is a television executive, host, and producer, known for his role as the host of Bravo's Watch What Happens Live. On Full Frontal with Samantha Bee, Cohen appeared as himself, lending his expertise and witty banter to the show's comedic segments.

Jane Fonda
as Self (1 episode)

Jane Fonda is an iconic actress and activist, known for her extensive filmography and dedication to social and political causes. On Full Frontal with Samantha Bee, Fonda appeared as herself, sharing her insights and engaging in humorous discussions about current affairs.

Jane Lynch
as Self (1 episode)

Jane Lynch is a versatile actress and comedian, recognized for her roles in TV shows like Glee and movies like The 40-Year-Old Virgin. On Full Frontal with Samantha Bee, Lynch made a guest appearance as herself, showcasing her comedic timing and witty improvisation.

Catherine O'Hara
as Self (1 episode)

Catherine O'Hara is a talented actress and comedian, known for her charismatic performances in films like Beetlejuice and Home Alone. On Full Frontal with Samantha Bee, O'Hara made an appearance as herself, contributing her delightful humor and charm to the show's comedic segments.

Tan France
as Self (1 episode)

Tan France is a fashion designer, television personality, and author, best known for his role as the fashion expert on the Netflix series Queer Eye. On Full Frontal with Samantha Bee, France appeared as himself, lending his fashion expertise and adding a touch of style to the show's segments.

Amber Ruffin
as Self (1 episode)
Andrew Rannells
as Self (1 episode)
Kyra Sedgwick
as Self (1 episode)
Trixie Mattel
as Self (1 episode)
Katya Zamolodchikova
as Self (1 episode)
David Koechner
as Self (1 episode)
Patton Oswalt
as Self (1 episode)
Tony Hale
as Self (1 episode)
Karamo Brown
as Self (1 episode)
Harvey Fierstein
as Self (1 episode)
Cynthia Erivo
as Self (1 episode)
Samm Henshaw
as Self - Musical Guest (1 episode)
Patrick Harvie
as Self (1 episode)
Bradley Whitford
as Self (1 episode)
Snooki
as Self (1 episode)
Michele Mitchell
as Self (1 episode)
Robert De Niro
as Self (1 episode)
Shepard Smith
as Self (1 episode)
Ludacris
as Self (1 episode)
Jon Ossoff
as Self (1 episode)
Jimmy Smits
as Dr. Fauci (1 episode)
Tim Gunn
as Self (2 episodes)
LaTosha Brown
as Self (1 episode)
James Monroe Iglehart
as Self (1 episode)
Will Arnett
as Self (1 episode)
Nicole Byer
as Self (1 episode)
Donald Faison
as Self (1 episode)
Juliana Hatfield
as Self (1 episode)
Jamaal Bowman
as Self (1 episode)
Cori Bush
as Self (1 episode)
Aly Michalka
as Self - Musical Guest (1 episode)
Cliff Albright
as Self (1 episode)
AJ Michalka
as Self - Musical Guest (1 episode)
Mondaire Jones
as Self (1 episode)
Eleanor Holmes Norton
as Self (1 episode)
David Luban
as Self (1 episode)
Jewel
as Self (1 episode)
Katie Porter
as Self (1 episode)
Michael Lewis
as Self (1 episode)
Elizabeth Warren
as Self (1 episode)
Kamala Harris
as Self (1 episode)
MILCK
as Self - Musical Guest (1 episode)
Ayanna Pressley
as Self (1 episode)
William J. Barber II
as Self (1 episode)
Lars Ulrich
as Self (1 episode)
Pramila Jayapal
as Self (1 episode)
Lawrence Wilkerson
as Self (1 episode)
Naomi Ekperigin
as Self (1 episode)
Feminista Jones
as Self (1 episode)
Talesha Wilson
as Self (1 episode)
April Ryan
as Self (1 episode)
Regina King
as Self (1 episode)
Amelia Meath
as Self - Musical Guest (1 episode)
Ilhan Omar
as Self (1 episode)
William Jackson Harper
as Self (1 episode)
Irene Tu
as Self (1 episode)
Bellamy Young
as Self (1 episode)
River Butcher
as Self (1 episode)
W. Kamau Bell
as Self (1 episode)
Grace Kuhlenschmidt
as Self (1 episode)
Ilana Glazer
as Self (1 episode)
Rachel Pegram
as Self (1 episode)
Nyle DiMarco
as Self (1 episode)
Tegan Quin
as Self (1 episode)
Sara Quin
as Self (1 episode)
Josh Groban
as Self (1 episode)
Shannon Watts
as Self (1 episode)
Richard Marx
as Self (1 episode)
Margaret Cho
as Self (1 episode)
Aparna Nancherla
as Self (1 episode)
Rebecca Black
as Self (1 episode)
Brian Bell
as Self (1 episode)
Jack Black
as Self (1 episode)
Kyle Gass
as Self (1 episode)
Gabby Giffords
as Self (1 episode)
Michael Imperioli
as Self (1 episode)
Lucia McBath
as Self (1 episode)
mxmtoon
as Self (1 episode)
Millicent Simmonds
as Self (1 episode)
Erin Foley
as Self (1 episode)
Tiya Sircar
as Self (1 episode)
Marque Richardson
as Self (1 episode)
Shungudzo
as Self - Musical Guest (1 episode)
Steve Buscemi
as Self (1 episode)
VINCINT
as Self - Musical Guest (1 episode)
Alex Newell
as Self - Musical Guest (1 episode)
June Diane Raphael
as Self (1 episode)
Dale Ho
as Self (1 episode)
Charity Dean
as Self (1 episode)
Vivian Howard
as Self (1 episode)
Jamie Eaddy
as Self (1 episode)
Lori Zaspel
as Self (1 episode)
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