Ethan Hawke (Self - Illustrious Guest) leads the Desus & Mero cast as the #68 ranked actor globally. Cast members below include current popularity rankings where available.
November 28, 2025

Top 10 Cast Members

Ranked by Wikipedia pageviews on November 27, 2025

Desus & Mero Full Cast

All 107 cast members with rankings based on Wikipedia pageviews