Ethan Hawke (Self - Illustrious Guest) leads the Desus & Mero cast as the #68 ranked actor globally. Cast members below include current popularity rankings where available.
November 28, 2025
Top 10 Cast Members
Ranked by Wikipedia pageviews on November 27, 2025
Desus & Mero Full Cast
All 107 cast members with rankings based on Wikipedia pageviews
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