Cast of Masters of Sex

Michael Sheen portrays the character of Dr. William Masters, a renowned fertility expert and a pioneer in the study of human sexuality.

Lizzy Caplan plays the role of Virginia Johnson, Dr. Masters' assistant and eventual research partner. Johnson becomes an influential figure in the field of sexual research.

Caitlin FitzGerald portrays the character of Libby Masters, Dr. Masters' wife. Libby struggles with her own desires and the challenges of their unconventional marriage.

Annaleigh Ashford plays the role of Betty DiMello, a sex worker who becomes an integral part of Dr. Masters and Virginia's research team.

Nicholas D'Agosto portrays the character of Dr. Ethan Haas, a young and ambitious doctor who joins Dr. Masters' team and becomes involved in their controversial research.

Teddy Sears plays the role of Dr. Austin Langham, another member of Dr. Masters' team who assists in their groundbreaking research.

Roslyn Ruff portrays the character of Josephine May, a patient of Dr. Masters who becomes an active participant in the research studies.

Margo Martindale plays the role of Miss Horchow, the head of the university library where Dr. Masters and Virginia conduct much of their research.