Brothers and Sisters (TV) Cast
The cast of Brothers and Sisters. Updated on July 28, 2025.
578 actors
Dave Annable
as Justin Walker (109 episodes)

Dave Annable plays Justin Walker, the youngest sibling in the Walker family who struggles with addiction and finding his path in life.

Sally Field
as Nora Walker (109 episodes)

Sally Field portrays Nora Walker, the strong and caring matriarch of the Walker family.

Calista Flockhart
as Kitty Walker (109 episodes)

Calista Flockhart is Kitty Walker, a successful career woman balancing her work and personal life.

Rachel Griffiths
as Sarah Walker (109 episodes)

Rachel Griffiths plays Sarah Walker, the eldest Walker sibling who deals with running a business and managing her family.

Matthew Rhys
as Kevin Walker (109 episodes)

Matthew Rhys is Kevin Walker, the dedicated and witty lawyer of the family.

Ron Rifkin
as Saul Holden (109 episodes)

Ron Rifkin portrays Saul Holden, Nora's brother who closely supports the family.

Emily VanCamp
as Rebecca Harper (109 episodes)

Emily VanCamp plays Rebecca Harper, a key figure who connects with the Walker family.

Luke Macfarlane
as Scotty Wandell (109 episodes)

Luke Macfarlane is Scotty Wandell, Kevin's husband whose relationship grows throughout the series.

Gilles Marini
as Luc Laurent (35 episodes)

Gilles Marini portrays Luc Laurent, a charming Frenchman who becomes Sarah's love interest.

Maxwell Perry Cotton
as Cooper Whedon (109 episodes)

Maxwell Perry Cotton plays Cooper Whedon, Sarah's young son.

Patricia Wettig
as Holly Harper (109 episodes)

Patricia Wettig is Holly Harper, a woman with deep connections to the Walker family.

Sarah Jane Morris
as Julia Walker (87 episodes)

Sarah Jane Morris portrays Julia Walker, wife of Tommy Walker.

Rob Lowe
as Robert McCallister (78 episodes)
John Pyper-Ferguson
as Joe Whedon (27 episodes)
Kerris Dorsey
as Paige Whedon (109 episodes)
Luke Grimes
as Ryan Lafferty (48 episodes)
Balthazar Getty
as Tommy Walker (109 episodes)
Parry Shen
as Dan Silk (2 episodes)
Margot Kidder
as Emily Craft (2 episodes)
Steven Weber
as Graham Finch (8 episodes)
Stana Katic
as Karen Wells (1 episode)
Joel Grey
as Dr. Jude Bar-Shalo (1 episode)
Ned Bellamy
as Cutler Weeks (1 episode)
Mitch Pileggi
as Browne Carter (3 episodes)
Christina Chang
as Professor Jane Condon (1 episode)
John Berg
as University President (1 episode)
Ned Vaughn
as Michael Gradstein (1 episode)
Christopher Allport
as Governor Michael Bryant (1 episode)
Diva Zappa
as Classmate #2 (1 episode)
Kim Murphy
as Donna Jones (1 episode)
Tom Virtue
as Dr. Bob Feldman (1 episode)
Sunkrish Bala
as Lewis (1 episode)
Caroline Aaron
as Elise (1 episode)
Matt Gallant
as The Reporter (1 episode)
Nigel Havers
as Roger Grant (6 episodes)
Karl T. Wright
as Alan Simms (1 episode)
Cheryl Hines
as Buffy McCreary (3 episodes)
Marin Hinkle
as Courtney McCallister (3 episodes)
Garry Marshall
as Major Jack Wiener (2 episodes)
Cotter Smith
as Gordon Alexander (2 episodes)
David Andrews
as George Lafferty (2 episodes)
Matthew Settle
as Jonathan Sellers (4 episodes)
Jon Tenney
as Dr. Simon Craig (5 episodes)
Treat Williams
as David Morton (4 episodes)
Peter Gerety
as Dennis York (11 episodes)
Marion Ross
as Ida Holden (3 episodes)
Matt Letscher
as Alec Tyler (5 episodes)
Maya Hazen
as Amy Chang (1 episode)
Tom McGowan
as Luther Reeves (1 episode)
Caroline Lagerfelt
as Jane (1 episode)
J. Grant Albrecht
as Joe Corvus (2 episodes)
Eric Pierpoint
as Stanley Hancock (1 episode)
Enrico Colantoni
as Evan (1 episode)
Ken Howard
as Boyd Taylor (1 episode)
Regis Philbin
as Regis Philbin (1 episode)
Jenna Elfman
as Lizzie Jones-Baker (1 episode)
Khamani Griffin
as Alex (1 episode)
Ryan Michelle Bathe
as Noreen (3 episodes)
John Rubinstein
as Dr. Marc Wilson (1 episode)
Ellery Sprayberry
as The Girl (1 episode)
Josh Stamberg
as Cliff (1 episode)
Eric Christian Olsen
as Kyle DeWitt (6 episodes)
Jerry Lambert
as Officer Phipps (1 episode)
Lawrence Mandley
as Sgt. Herrell (1 episode)
Emilio Rivera
as The Sponsor (1 episode)
Marguerite Moreau
as Ginny Lawford (2 episodes)
Kaitlin Doubleday
as Chelsea Yeager (2 episodes)
Michael B. Silver
as Stu Orenbacher (2 episodes)
Laraine Newman
as Lyla (2 episodes)
D.W. Moffett
as Michael Pellington (1 episode)
Will McCormack
as Ethan Tavis (6 episodes)
Darcy Rose Byrnes
as Gwyneth (1 episode)
Ryan Eggold
as Randy Stewart (1 episode)
Jason Lewis
as Chad Barry (8 episodes)
Michael O'Keefe
as Wally Wandell (3 episodes)
Denzel Whitaker
as Carter (3 episodes)
Sarah Lilly
as D.A. (1 episode)
Michael Nouri
as Milo Peterman (3 episodes)
Emily Rose
as Lena Branigan (10 episodes)
Nathan Keyes
as Sam (1 episode)
Tom Skerritt
as William Walker (7 episodes)
Tyrees Allen
as Dr. John Massey (2 episodes)
Romy Rosemont
as The Counselor (2 episodes)
Maura Soden
as Dr. Barbara Riley (2 episodes)
Keri Lynn Pratt
as Amber Trachtenberg (4 episodes)
Evie Peck
as Gail (1 episode)
David Paymer
as Donald Dudley (1 episode)
Mark Daniel Cade
as (1 episode)
Rachel Montez Collins
as L.A. Babe (1 episode)
John Benjamin Hickey
as Major Guinness (1 episode)
Phill Lewis
as Dr. Peter Edwards (1 episode)
Danny Glover
as Isaac Marshall (6 episodes)
Kelly Ripa
as Kelly Ripa (1 episode)
Lyle Lovett
as Lyle Lovett (1 episode)
Suzanne Whang
as Carly (1 episode)
Sonja Sohn
as Trish Evans (4 episodes)
Joe Morton
as Peter Madsen (2 episodes)
Denis O'Hare
as Travis March (12 episodes)
Chevy Chase
as Stan Harris (2 episodes)
John Glover
as Henry Mittner (1 episode)
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