House

Hugh Laurie portrays the brilliant and misanthropic Dr. Gregory House. Dr. House is a diagnostic genius who often clashes with his colleagues due to his unconventional methods and blunt demeanor.

Lisa Edelstein plays the role of Dr. Lisa Cuddy, the Dean of Medicine and Hospital Administrator at Princeton-Plainsboro Teaching Hospital. Dr. Cuddy is tasked with managing the hospital and dealing with the challenges that come with overseeing Dr. House's team.

Robert Sean Leonard portrays Dr. James Wilson, a close friend of Dr. House and the head of the Oncology Department at the hospital. Dr. Wilson often provides emotional support to Dr. House and is his sounding board for medical cases.

Omar Epps plays the role of Dr. Eric Foreman, a member of Dr. House's diagnostic team. Dr. Foreman is a capable and ambitious doctor who often challenges Dr. House's decisions and methods.

Jennifer Morrison portrays Dr. Allison Cameron, a talented immunologist and member of Dr. House's team. Dr. Cameron is known for her compassion towards patients and often has a more ethical approach to medicine compared to Dr. House.

Jesse Spencer plays the role of Dr. Robert Chase, an Australian doctor and member of Dr. House's team. Dr. Chase often takes on risky procedures and is known for his good looks and charm.

Odette Annable portrays Dr. Jessica Adams, a talented and intelligent doctor who joins Dr. House's team in later seasons. Dr. Adams brings a fresh perspective to the team and often challenges their assumptions.

Peter Jacobson plays the role of Dr. Chris Taub, a plastic surgeon who joins Dr. House's team. Dr. Taub is known for his sarcastic sense of humor and occasionally clashes with his colleagues.