Cast of The Simpsons

Dan Castellaneta provides the voices for several main characters on The Simpsons, including Homer Simpson, the bumbling and lovable father of the family; Abe Simpson, Homer's elderly and often senile father; Barney Gumble, Homer's beer-loving friend; and Krusty the Clown, the children's entertainer and host of a popular variety show.

Julie Kavner lends her voice to three important characters on The Simpsons. She voices Marge Simpson, the patient and caring matriarch of the family; as well as Patty and Selma Bouvier, Marge's older twin sisters who are known for their cynicism and disdain for Homer.

Nancy Cartwright is responsible for bringing to life several iconic characters on The Simpsons, including Bart Simpson, the mischievous and troublemaking eldest son of the family; Nelson Muntz, the school bully with a distinctive laugh; and Ralph Wiggum, the clueless and often bizarre classmate of Bart and Lisa.

Yeardley Smith provides the voice for the intelligent and compassionate Lisa Simpson, the middle child of the family. Lisa is known for her activism, strong moral compass, and her talent for playing the saxophone.

Hank Azaria is the voice behind several recurring characters on The Simpsons, including Moe Szyslak, the grumpy and perpetually single owner of Moe's Tavern; Chief Wiggum, the dimwitted and incompetent police chief of Springfield; Apu Nahasapeemapetilon, the Indian immigrant who runs the Kwik-E-Mart; Comic Book Guy, the overweight and socially awkward comic book store owner; and Carl Carlson, one of Homer's friends and coworkers at the nuclear power plant.

Harry Shearer voices a number of key characters on The Simpsons, including Ned Flanders, the overly friendly and devoutly religious neighbor of the Simpsons; Mr. Burns, the wealthy and morally bankrupt owner of the nuclear power plant; Waylon Smithers, Mr. Burns' loyal assistant; Principal Seymour Skinner, the strict and often inept school principal; and Lenny Leonard, one of Homer's friends and coworkers at the power plant.

Gillian Anderson is a guest voice actress on The Simpsons, known for her role as Dana Scully on The X-Files. She has made appearances as various characters throughout the show's run.

Johnny Cash, the legendary country music singer, provided the voice for the character Space Coyote in a memorable episode of The Simpsons. Space Coyote appears in a hallucination experienced by Homer Simpson and offers him guidance during a spiritual journey.